Premium
Postnatal outcome of prenatally diagnosed severe fetal renal pelvic dilatation
Author(s) -
Kumar Sailesh,
Walia Shikha,
Ikpeme Obori,
Zhang Eko,
Paramasivam Gowrishankar,
Agarwal Sanjiv,
Murphy Karl,
Deal Jane,
Lakasing Lorin
Publication year - 2012
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.2893
Subject(s) - medicine , surgery , prenatal diagnosis , cohort , fetus , retrospective cohort study , pregnancy , biology , genetics
Objective We correlated the prenatal severity with the postnatal outcome of prenatally detected renal pelvic dilatation (RPD). Methods Cases of prenatally detected RPD referred between January 2002 and December 2008 were included. Severe RPD was defined as an anterior–posterior diameter of 15 mm, mild and moderate dilatation was defined as 6 to <10 mm and 10 to <15 mm, respectively. Postnatal diagnosis, the need for surgery and the correlation with the prenatal severity was ascertained. Results Of the 762 patients with RPD, 492 (64.5%) were mild, 167 (21.9%) were moderate, and 103 (13.5%) were severe. The male:female ratio for the severe cohort was 5:1. Of the sever cases, 68% had progressive dilatation. Of the mild/moderate cases, 5% progressed to severe dilatation. PUJ obstruction was confirmed in 48 cases (60.8%), severe VUR in 11 cases (14%), VUJ obstruction in 5 cases (6%), PUV in 2 cases (2.5%), and a nonidentifiable cause in 13 cases (16.5%). Ten of the 48 (20.8%) babies with PUJ obstruction required surgery within the first year of life. Conclusion An obstructive cause is usually present in severe cases, which are more likely to require surgery if there is PUJ obstruction. A high male:female ratio was present in this group. © 2012 John Wiley & Sons, Ltd.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom