Premium
Intrinsic specificity of Ca 2+ –protein binding sites
Author(s) -
Reiter Alex,
Zhao Hong,
Adams Jeanette
Publication year - 1993
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210281235
Subject(s) - chemistry , peptide , gas phase , metal , decomposition , alkaline earth metal , fast atom bombardment , ion , phase (matter) , atom (system on chip) , inorganic chemistry , crystallography , stereochemistry , organic chemistry , biochemistry , computer science , embedded system
Abstract The gas‐phase chemistry of anionic [M + Cat 2+ – 3H] − complexes between Ca 2+ ‐specific peptides and the alkaline earth metal ions Mg 2+ , Ca 2+ and Ba 2+ is reported. The metal ion complexes were studied using fast atom bombardment, collision‐induced decomposition (CID) and molecular mechanical calculations. The CID reactions and molecular mechanical calculations revealed that the Ca 2+ –peptide complexes are bound differently to the Mg 2+ – and Ba 2+ –peptide complexes and that the intrinsic (gas‐phase) chemistry is reflected by known aqueousphase chemistry.