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Poly(vinyl alcohol) Cryogel Formation Using Biocompatible Ice Nucleating Agents
Author(s) -
Jiang Yanjiao,
Hussain Hazrat,
Kressler Joerg
Publication year - 2015
Publication title -
macromolecular materials and engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 96
eISSN - 1439-2054
pISSN - 1438-7492
DOI - 10.1002/mame.201400229
Subject(s) - vinyl alcohol , materials science , biocompatible material , aqueous solution , supercooling , nucleation , ice nucleus , chemical engineering , rheology , alcohol , polymer chemistry , organic chemistry , composite material , polymer , chemistry , biomedical engineering , medicine , physics , thermodynamics , engineering
To control the influence of supercooling on the preparation of poly(vinyl alcohol) (PVA) cryogel, various biocompatible ice nucleating agents, including, two fatty alcohols, and eight different amino acids are investigated for their ice nucleating efficiency in PVA aqueous solutions. The L ‐aspartic acid is found to be the most efficient ice nucleating agent with the ability to induce freezing at ∼−5.5 °C in 8.3 wt% aqueous PVA solution as compared to ∼−20 °C without L ‐aspartic acid. The PVA cryogels are prepared with L ‐aspartic acid as the heterogeneous ice nucleating agent and investigated for their rheological properties. Finally, it is found that freezing temperature close to the sol–gel transition temperature produces cryogel with the high tack important for various biomedical applications.
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