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Tumor Mapping: New Rationales, Adjusted Techniques, Expanded Applications
Author(s) -
Cinberg Jim Z.,
Katlein Stanley B.,
Vogl Steven E.
Publication year - 1983
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1002/lary.1983.93.10.1285
Subject(s) - medicine , radiation therapy , induction chemotherapy , chemotherapy , surgical resection , surgery , oral cavity , induction therapy , oncology , radiology , orthodontics
Eleven consecutive patients with cancers of the oropharynx (4), hypopharynx (4), and oral cavity (3) were endoscoped and “tumor mapped” with a modified tattoo solution before beginning non‐surgical antineoplastic therapy. The tattooed outlines were clearly visible at 7 weeks (5 patients after induction chemotherapy); at 14 weeks (2 patients after induction chemotherapy and radiotherapy); and between 12 and 16 weeks (4 patients after radiotherapy). The “tumor mapping” aided both the establishment of appropriate resection margins in cancers that had diminished in response to non‐surgical therapy and the recognition of a tumor's lack of response to nonsurgical antineoplastic treatment.