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Distribution of tritium label in Dl‐[G‐3H] phenylalanine
Author(s) -
Clifford Merwyn C.,
Evans E. Anthony,
Kilner A. Edward,
Warrell David C.
Publication year - 1975
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590110319
Subject(s) - tritium , phenylalanine , chemistry , radiochemistry , tritiated water , nuclear chemistry , biochemistry , nuclear physics , amino acid , physics
The position of the tritium label in DL‐[G‐3H] phenylalanine prepared by platinum catalysed exchange in tritiated water at elevated temperatures has been determined by chemical degradation and by tritium nuclear magnetic resonance speotroscopy. There is good agreement between the results of the two methods : analysis of the product of two separate preparations showing 73 ± 3% of the activity in the aromatic nucleus and 27 ± 3% in the side chain.