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The synthesis of 14 C‐trans‐3‐methyl‐2‐hexenoic acid labeled in various positions
Author(s) -
Rabinowitz Joseph L.,
Zanger Murray
Publication year - 1972
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590080414
Subject(s) - chemistry , methyl iodide , iodide , stereochemistry , medicinal chemistry , organic chemistry
The Emmons reaction was used for the synthesis of 14 C‐ trans ‐3‐methyl‐2‐hexenoic acid. This compound is found in human sweat. 1‐ 14 C‐2‐pentanone was prepared by the reaction at room temperature of 14 C‐methyl‐magnesium iodide and butyronitrile.