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Synthesis of tritium labeled isoxsuprine hydrochloride
Author(s) -
Madding G. D.
Publication year - 1971
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590070402
Subject(s) - tritium , propiophenone , hydrochloride , chemistry , radiochemistry , organic chemistry , ketone , physics , nuclear physics
Tritium labeled isoxsuprine hydrochloride was required for drug metabolism studies in these laboratories. This compound was prepared specifically labeled with tritium in the 1‐position by the catalytic reduction of racemic β(R), γ(R)‐ and β(S), γ(S)‐p‐hydroxy‐α‐(1‐phenoxy‐2‐propylamino)‐propiophenone hydrochloride with tritium.