Premium
Synthesis of labeled o‐iodohippuric acid
Author(s) -
Wheeler O. H.,
Verter H. S.,
Feliú L. A.,
De Jesús C. R.
Publication year - 1971
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590070107
Subject(s) - anthranilic acid , chemistry , iodide , ion exchange , organic chemistry , ion
The reaction of o‐iodohippuric acid with labeled iodide has been shown to afford exclusively labeled o‐iodohippuric acid. The same compound has been synthesized from anthranilic acid. The rate of exchange was sufficiently rapid to permit the preparation of 132 I and 128 I labeled o‐iodohippuric acid. The mechanism of the exchange is discussed.