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Synthesis of carbon‐14 labeled isocyanates. Determination of the carbon‐14 distribution in the isocyanate groups of 2, 4‐tolylene diisocyanate
Author(s) -
Kopka E. F.,
Rapp N. Sue,
Ingham J. D.
Publication year - 1965
Publication title -
journal of labelled compounds
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0022-2135
DOI - 10.1002/jlcr.2590010309
Subject(s) - isocyanate , chemistry , polymer chemistry , organic chemistry , polyurethane
A practical phosgenation procedure has been devised for the preparation of isocyanates labeled with 14 C. Three such isocyanates: 2‐tolyl isocyanate, 4‐tolyl isocyanate, and 2, 4‐tolylene diisocyanate (TDI) were prepared. The 14 C distribution in the latter was determined by scintillation counting of some of its derivatives, one of which was 3‐amino‐4, 2′, 6′‐trimethylcarbanilide, from which the fraction of 14 C in the 4‐isocyanate group of TDI was obtained.