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Carbon‐11 labelling of a half mustard prodrug by reductive alkylation using [ 11 C]acetaldehyde. A potential tracer for evaluation of adept or gdept using pet
Author(s) -
Khanum N.,
Luthra S. K.,
Zhao Y.,
Aboagye E.,
Price P. M.,
Burke P.,
Brady F.
Publication year - 2001
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.25804401112
Subject(s) - chemistry , acetaldehyde , alkylation , prodrug , labelling , radiochemistry , organic chemistry , ethanol , biochemistry , catalysis
A half mustard anticancer prodrug carrying N ‐chloroethyl and N ′‐ethyl groups was labelled in the N ′‐ethyl group by reductive alkylation using [ 11 C]acetaldehyde.