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Fluorine‐substituted ligands for the peroxisome proliferator‐activated receptor gamma (Pparγ): Potential imaging agents for metastatic tumors
Author(s) -
Kim S. H.,
Jonson S. D.,
Welch M. J.,
Katzenellenbogen J. A.
Publication year - 2001
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.25804401111
Subject(s) - chemistry , peroxisome proliferator activated receptor , in vivo , receptor , in vitro , peroxisome proliferator activated receptor gamma , nuclear receptor , peroxisome proliferator activated receptor alpha , cancer research , pharmacology , biochemistry , transcription factor , biology , microbiology and biotechnology , gene
Fluorine‐substituted analogs of ligands for the peroxisome proliferator‐activated receptor gamma (PPARγ), a new target for tumors imaging, retained receptor binding affinity in vitro, but did not show receptor‐mediated uptake in vivo.