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Synthesis of deuterium‐labeled acrivastine and an acrivastine metabolite
Author(s) -
Thompson J. B.,
Blake K. W.,
McNutt R. W.
Publication year - 1995
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580361009
Subject(s) - chemistry , metabolite , chromatography , deuterium , mass spectrometry , gas chromatography , biochemistry , physics , quantum mechanics
The antihistamine acrivastine and a metabolite dihydroacrivastine were prepared as their [ 2 H 7 ]‐congeners from [ 2 H 8 ]‐tolualdehyde for use as internal standards in gas chromatography/mass spectroscopy of biological samples.