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Synthesis of non ‐ carrier added [N ‐ methyl ‐ 11 C] roxithromycine
Author(s) -
Barre L.,
Lasne M. C.,
Charbonneau P.
Publication year - 1995
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580360812
Subject(s) - chemistry , yield (engineering) , positron emission tomography , radiochemistry , antibiotics , nuclear chemistry , nuclear medicine , biochemistry , medicine , materials science , metallurgy
Roxithromycine, a new macrolide, was labelled with [ 11 C]CH 3 I in a good radiochemical yield (40‐45%)and high specific activities (500‐550mCi/μmol). This antibiotic may be useful for detecting pulmonar or cerebral infection foci using positron emission tomography.