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Esters of 6‐(4′‐fluorobenzylamino)‐β‐ carboline‐3‐carboxylic acid as potential benzodiazepine imaging agents for P.E.T.
Author(s) -
Elder S. T.,
Mach R. H.,
Nowak P. A.,
Moroney D. A.,
Rao A. V.,
Ehrenkaufer R. L. E.
Publication year - 1995
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580360302
Subject(s) - chemistry , benzodiazepine , carboxylic acid , amine gas treating , iodide , alkylation , gabaa receptor , medicinal chemistry , receptor , tertiary amine , stereochemistry , combinatorial chemistry , organic chemistry , biochemistry , catalysis
As potential P.E.T. imaging agents for the benzodiazepine receptor, two fluorine‐ 18 labeled analogues of the β‐carbolines were prepared via N‐ alkylation of the corresponding desbenzyl amine precursors with [ 18 F]fluorobenzyl iodide.