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Synthesis of cyano‐[D 11 ]‐cyclohexane
Author(s) -
Abenhaim D.,
Loupy A.,
Petit A.,
GonthierVassal A.,
Szwarc H.
Publication year - 1993
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580330106
Subject(s) - chemistry , cyclohexanol , cyclohexane , nitrile , yield (engineering) , alcohol , chloride , organic chemistry , nuclear chemistry , medicinal chemistry , catalysis , materials science , metallurgy
Cyano‐[D 11 ]‐cyclohexane was prepared from commercial [D 12 ]‐cyclohexanol via the sequence alcohol‐chloride‐acid‐nitrile in an overall yield of 33% after purification. Isotopic purity was at least 98%.