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Synthesis of [16‐ 14 C]trichodiene the precursor to trichothecenes
Author(s) -
Zamir Lolita O.,
Huang Liren
Publication year - 1992
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580311110
Subject(s) - chemistry , wittig reaction , reagent , phosphine , isotope , radiochemistry , chemical synthesis , carbon 14 , organic chemistry , stereochemistry , catalysis , biochemistry , physics , quantum mechanics , in vitro
The synthesis of radiolabelled trichodiene with 14 C at the olefinic methyl (C‐16) is described. The isotope was introduced using a 14 C‐Wittig reagent prepared in situ from triphenyl phosphine and 14 C‐methyliodide.