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Use of tritiated methylborane in the synthesis of labelled primary amines
Author(s) -
Burgos Alain,
Kamenka JeanMarc,
Rousseau Bernard
Publication year - 1991
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580291212
Subject(s) - chemistry , tritium , tritiated water , yield (engineering) , tritium illumination , radiochemistry , primary (astronomy) , specific activity , carbon 14 , organic chemistry , enzyme , physics , astronomy , nuclear physics , materials science , quantum mechanics , metallurgy
Abstract Tritiated methylborane prepared from tritium gas and methaneboronic acid was used to prepare [2‐H 3 ]‐trans‐2‐phenylcyclopentylamine from 1‐phenylcyclopentene with a high specific activity (26Ci/mmol) in 20–40% yield.