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Synthesis of [methyl‐ 2 H]‐labelled ajmalicine, yohimbine, tabersonine and catharanthine
Author(s) -
Auriola S.,
Naaranlahti T.,
Lapinjoki S. P.
Publication year - 1991
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580290116
Subject(s) - chemistry , transesterification , methanol , yohimbine , deuterium , organic chemistry , stereochemistry , biochemistry , physics , receptor , quantum mechanics , antagonist
Deuterium labelled analogues of ajmalicine, yohimbine, tabersonine and catharanthine were synthesized by base catalyzed transesterification of the methyl group in deuterated methanol.