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Iron‐59 labelled sodium nitroprusside
Author(s) -
Bates J. N.
Publication year - 1990
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580280416
Subject(s) - chemistry , sodium nitroprusside , sodium nitrite , ferrous , sodium , chromatography , high performance liquid chromatography , chloride , potassium cyanide , ion chromatography , potassium , ion exchange , radiochemistry , cyanide , ion , inorganic chemistry , organic chemistry , nitric oxide
Sodium nitroprusside, a potent vasodilator in man, is synthesized with the gamma‐emitting isotope 59 Fe in a single‐step synthesis from potassium cyanide, sodium nitrite, and ferrous chloride. It is purified by anion exchange chromatography and assayed by ion‐pair high pressure liquid chromatography. 14 C‐nitroprusside is prepared by the same methods.