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Radiosynthesis of 15 O‐labeled hydrogen peroxide
Author(s) -
Takahashi K.,
Murakami M.,
Hagami E.,
Sasaki H.,
Kondo Y.,
Mizusawa S.,
Nakamichi H.,
Iida H.,
Miura S.,
Kanno I.,
Uemura K.
Publication year - 1989
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580271008
Subject(s) - chemistry , radiosynthesis , autoxidation , hydrogen peroxide , radiochemistry , hydrogen , halogen , cyclotron , oxygen , nuclear chemistry , organic chemistry , ion , alkyl , nuclear medicine , positron emission tomography , medicine
15 O‐H 2 O 2 is thought to be a candidate of attractive injectable tracers for the study of oxygen metabolism with PET. A simple synthetic method yielding 15 O‐H 2 O 2 in saline solution by the autoxidation of 2‐ethylanthrahydroquinol with gaseous 15 O‐O 2 produced by cyclotron target system is described.