Premium
Phase transfer mediated synthesis of radiolabelled alkyl aryl ethers and sulphides
Author(s) -
Bergman Åke,
Wachtmeister Carl Axel
Publication year - 1987
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580240807
Subject(s) - chemistry , iodide , alkyl , catalysis , aryl , phenols , methyl iodide , organic chemistry , phase (matter) , tritium , physics , nuclear physics
Tritium‐ or 14 C‐labelled methyl iodide and ethyl iodide were used for alkylations of phenols and thiols. The reactions were performed in a two‐phase system with phase transfer catalysis at room temperature. Products of high specific activity were isolated in isotope yields ranging from 38% to 100%.