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Convenient one‐pot synthesis of benzoquinone‐[U‐ 14 c] and hydroquinone‐[U‐ 14 c]
Author(s) -
Parnes Howard,
Dekeczer Steve
Publication year - 1986
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580230711
Subject(s) - hydroquinone , chemistry , yield (engineering) , benzene , benzoquinone , quinone , medicinal chemistry , radiochemistry , organic chemistry , metallurgy , materials science
Abstract Benzoguinone‐[U‐ 14 C] was synthesized in 90% yield from benzene‐[U‐ 14 C] via a three step seguence. Conditions were developed which allowed this conversion to be accomplished in a one pot closed system. The benzoquinone‐[U‐ 14 C] thus obtained could be reduced to hydroquinone‐[U‐ 14 C] in quantitative yield. Preparation of benzene‐[U‐ 14 C] is also described.