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Synthesis of carbon‐14 labeled clomiphene
Author(s) -
Rao P. Narasimha,
Cessac James W.
Publication year - 1985
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580220306
Subject(s) - chemistry , antiestrogen , derivative (finance) , carbon 14 , carbon fibers , nonsteroidal , stereochemistry , medicinal chemistry , combinatorial chemistry , pharmacology , medicine , tamoxifen , physics , materials science , cancer , quantum mechanics , breast cancer , composite number , economics , financial economics , composite material
Clomiphene, 2‐[4‐(2‐chloro‐1,2‐diphenylethenyl)phenoxy]‐N, N‐diethylethanamine, an antiestrogen, is a nonsteroidal triphenylethylene derivative. For the successful synthesis of carbon‐14 labeled clomiphene it is essential to have a free radical inhibitor in the reaction medium.