Premium
Preparation de l'acide méso diamino‐2, 6 heptane‐dioique‐1, 7‐[ 3 H‐3, 4, 5] (méso‐diamino pimelique‐[ 3 H‐3, 4, 5])
Author(s) -
Schott D.,
Rousseau B.,
Beaucourt J. P.,
Lellouche J. P.,
Pichat L.
Publication year - 1985
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580220205
Subject(s) - chemistry , dehydrohalogenation , methanol , thin layer chromatography , heptane , catalysis , medicinal chemistry , cellulose , nuclear chemistry , organic chemistry
Meso 2, 6‐diamino [ 3 H‐3, 4, 5] 1, 7‐heptanedioc acid‐ (meso [ 3 H‐3, 4, 5] DAP) specific activity 30 Ci/mM was obtained by catalytic dehydrohalogenation of meso 3‐chloro and 4‐chloro DAP. LL, DD and meso DAP were analytically separated by cellulose thin layer chromatography (methanol‐water‐7 : 3).