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Synthesis and characterization of cis and trans ‐4‐d −1 ‐1‐tetralol
Author(s) -
Groenewold G. S.,
Gross M. L.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580181214
Subject(s) - chemistry , lithium (medication) , characterization (materials science) , nuclear magnetic resonance spectroscopy , stereochemistry , nanotechnology , medicine , materials science
Trans ‐4‐d −1 ‐tetranydronaphthalen‐1‐ol ( trans ‐4‐d −1 ‐1‐ tetralol) was synthesized from 1,4‐epoxy‐1,2,3,4‐ tetrahydronaphthalene using lithium tri‐ tert ‐butoxyaluminodeuteride. Cis ‐4‐d −1 ‐1‐tetralol was made by epimerizing the trans ‐ compound. Both compounds were characterized by high field 360 MHz NMR spectroscopy.