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Syntheses du Bergaptene [0 — methyl 14 C et 3 H] et de la Tabernanthine [0‐methyl 14 C]
Author(s) -
Bac N. V.,
Audinot M.,
Pichat L.,
Herbert M.,
Xuong N. Dat
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580181116
Subject(s) - methyl iodide , chemistry , iodide , radiochemistry , yield (engineering) , medicinal chemistry , organic chemistry , physics , thermodynamics
{0‐methyl 14 C} and {0‐methyl 3 H} bergaptene were prepared by methylation of bergaptol with { 14 C} methyl iodide and { 3 H} methyl iodide in radioactive yields respectively 77 % and 59 %. { 14 C} methyl iodide and 11‐hydroxy ibogamine gave {0‐methyl C} tabernanthine with a 60 % radioactive yield.