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Synthesis of 1‐pyrenyloxirane‐3,6,8‐ 3 H 1
Author(s) -
McCaustland Daniel J.,
Susàn Alexander B.,
Wiley James C.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580181010
Subject(s) - chemistry , yield (engineering) , pyrene , chemical synthesis , tritium , tritiated water , radiochemistry , combinatorial chemistry , organic chemistry , biochemistry , in vitro , materials science , physics , nuclear physics , metallurgy
The syntheses of 1‐pyrenyloxirane‐3,6,8‐ 3 H 1 , 7 , and its precursor, pyrene‐1,3,6,8‐ 3 H 1 , 4 , are described. The synthesis pathway includes a novel preparation of 4 from 1‐pyrenyllithium and tritiated water in theoretical yield.