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Synthesis of specifically‐deuterated procaine and tetracaine
Author(s) -
Boulanger Yvan,
Leitcht Leonard C.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180815
Subject(s) - tetracaine , chemistry , procaine , deuterium , pharmacology , neuroscience , nuclear physics , lidocaine , psychology , medicine , physics
Local anesthetics procaine and tetracaine have been specifically‐deuterated in two and three positions, respectively, for use in deuterium nuclear magnetic resonance experiments. The experimental procedure is either new or an adaptation of early synthetic methods.