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Potential drugs labelled with 14 C. II. Synthesis of 1‐cyano‐3‐imino‐8, 9‐dimethoxy‐3, 4,5,6‐ ‐tetrahydro‐thiazolo[4, 3‐a]isoquinoline hydrochloride
Author(s) -
Koltai E.,
Zólyomi G.,
Komáromy P.,
Bánfi D.,
Szüts T.,
Takács K.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180804
Subject(s) - isoquinoline , chemistry , hydrochloride , position (finance) , stereochemistry , medicinal chemistry , organic chemistry , finance , economics
The synthesis of 1‐cyano‐3‐imino‐8,9‐dimethoxy‐ ‐3,4, 5,6‐tetrahydro‐thiazolo [4,3‐a]isoquinoline hydrochloride labelled with 14 C in five different positions: in position 3 ( 1a ), in the cyano group at position 1 ( 1b ), in position 5 ( 1c ), in position 10b ( 1d ) and in the methoxy groups at position 8 and 9 ( 1e ) was carried out.