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Synthesis of 4‐amino‐3,2′ ‐dimethylbiphenyl‐3‐methyl‐ 14 C and 4‐amino‐2′‐methylbiphenyl‐2′‐methyl‐ 14 C
Author(s) -
ElBayoumy Karam,
Hecht Stephen S.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180707
Subject(s) - chemistry , biphenyl , mutagen , amino acid , stereochemistry , medicinal chemistry , carcinogen , organic chemistry , biochemistry
Abstract The syntheses of 4‐amino‐3,2′‐dimethyl‐biphenyl‐3‐methyl‐ 14 C, a potent carcinogen and mutagen, and 4‐amino‐2′‐methylbiphenyl‐2′‐methyl‐ 14 C, an analogue having weaker activity, are described. In both cases, label was introduced with Cu 14 CN.