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A simple synthesis of propionic‐3‐ 14 C acid
Author(s) -
Koltai E.,
Bánfi D.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180607
Subject(s) - chemistry , malonic acid , hydrolysis , derivative (finance) , methylation , organic chemistry , chemical synthesis , combinatorial chemistry , medicinal chemistry , biochemistry , in vitro , financial economics , economics , gene
Propionic‐3‐ 14 C acid was prepared by methylation of tricarbethoxymethane and subsequent hydrolysis. This method avoids the problems of malonic ester synthesis. A pure monoalkyl derivative was obtained.