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Synthesis of deuterated and tritiated derivatives of enflurane
Author(s) -
Burke Terrence R.,
Pohl Lance R.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180507
Subject(s) - chemistry , deuterium , tritium , radiochemistry , tritiated water , enflurane , organic chemistry , nuclear physics , physics , halothane
Specifically deuterated derivatives of the inhalation anesthetic enflurane [2‐chloro‐1‐(difluoromethoxy)‐1,1,2‐trifluoroethane] have been synthesized by a facile base catalyzed exchange. Tritiated enflurane has also been synthesized by this procedure.