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Synthesis of [1‐ 14 C]n‐heptane
Author(s) -
David G. G.,
Morris D. F. C.,
Short E. L.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180419
Subject(s) - heptane , yield (engineering) , bromide , chemistry , magnesium bromide , magnesium , carbon fibers , carbon dioxide , nuclear chemistry , medicinal chemistry , organic chemistry , materials science , metallurgy , composite number , composite material
Synthesis of n‐heptane labelled with carbon‐14 in the 1‐position is described. The precedure involves five steps starting with reaction of [ 14 C]carbon dioxide with n‐hexyl magnesium bromide and finishing with reduction of [1‐ 14 C]n‐heptyl bromide. The purity of the final product was more than 97% and the overall yield was 36%.