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Synthesis of indium‐111 mesoprotoporphyrin IX
Author(s) -
Lee K. M.,
Marshall A. G.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180309
Subject(s) - chemistry , indium , acetic acid , sodium acetate , heme , nuclear chemistry , sodium , inorganic chemistry , radiochemistry , organic chemistry , enzyme
Indium‐111 mesoprotoporphyrin IX has been prepared by refluxing suitable proportions of InCl 3 , sodium acetate, and mesoprotoporphyrin IX in glacial acetic acid. The labeled metalloporphyrin is sufficiently water‐soluble for use as a scanning agent, and can also be incorporated into heme apoproteins for perturbed gamma‐gamma angular correlation measurements.