Premium
Production of 13 N‐labelled molecular nitrogen for pulmonary function studies
Author(s) -
Vaalburg W.,
Steenhoek A.,
Paans A. M. J.,
Peset R.,
Reiffers S.,
Woldring M. G.
Publication year - 1981
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580180304
Subject(s) - chemistry , nitrogen , radiochemistry , irradiation , nuclear chemistry , organic chemistry , nuclear physics , physics
A method for the production of 13 NN either as a gas or as an injectable solution is described. The method is based on the 16 O(p,α) 13 N reaction and water as target material. Following irradiation, the 13 NO 2 −and 13 NO 3 −are reduced to 13 NH 3 , followed by NaOBr oxidation to 13 NN. With a beam current of 1 μA and 20 min irradiation time the injectable solution contained 148 MBq (4 mCi) per ml.