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Tritium labelling and tritium N.M.R. ‐ part I alpha‐labelled stearic, palmitic, myristic and lauric acids
Author(s) -
Crossley P. C.,
Martin R. W.,
Mawson J. B.,
Odell A. L.
Publication year - 1980
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580170604
Subject(s) - chemistry , tritium , myristic acid , labelling , palmitic acid , lauric acid , stearic acid , carbon 14 , radiochemistry , nuclear chemistry , tritium illumination , carbonylation , sodium hydroxide , organic chemistry , catalysis , fatty acid , carbon monoxide , biochemistry , physics , quantum mechanics , nuclear physics
Stearic, palmitic, myristic and lauric acids have been labelled with tritium in the alpha carbon position, and the position of the label confirmed using tritium N.M.R. spectrometry. The α‐ 3 H acids were prepared using tritiated water with sulphuric acid or sodium hydroxide as catalysts. Specifically labelled compounds of high specific activity and radiochemical purity were obtained.