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Syntheses De γ, γ‐Dimethyl α‐Methylene‐γ‐ Butyrolactone Et d'oxa‐1 Spiro [4,5] Methylene‐3 Decanone‐2 Marquees Au Carbone‐14
Author(s) -
Schlewer Gilbert,
Stampf JeanLuc,
Benezra Claude
Publication year - 1980
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580170217
Subject(s) - chemistry , methylene , cyclohexanone , acetone , medicinal chemistry , organic chemistry , catalysis
14 C‐labelled γ, γ‐dimethyl‐α‐methylene‐γ‐butyrolactone 1 and 1‐oxa‐Spiro [4.5]‐3‐methylene‐2‐decanone 2 have been synthesized from acetone and cyclohexanone respectively and 14 C‐labelled ethyl bromomethacrylate (Réformatsky reaction). The synthesis of this last compound is also described.