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Synthesis of 3‐cyano‐4‐methyl‐5( 14 C)‐methyl‐2‐(5‐ 14 C)pyrrolyloxamic acid
Author(s) -
Honigberg I. L.,
Meltzer N. M.,
Blanton C. D.
Publication year - 1979
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580160602
Subject(s) - chemistry , yield (engineering) , alanine , carbon 14 , medicinal chemistry , stereochemistry , amino acid , biochemistry , materials science , metallurgy , physics , quantum mechanics
Abstract A synthesis of 3‐cyano‐4‐methyl‐5 ( 14 C)‐methyl‐2‐(5‐ 14 C)pyrrolyloxamic acid is described. The compound, having specific activity of 66.7 μCi/mmole, was obtained in 19.68% overall yield from uniformly labelled 14 C‐L‐alanine.