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A two‐step synthesis of benzylamine‐ 15 N from ammonia‐ 15 N
Author(s) -
Gazzola C.,
Kenyon G. L.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580150124
Subject(s) - benzylamine , chemistry , sodium cyanoborohydride , yield (engineering) , benzaldehyde , ammonia , methanol , solvent , organic chemistry , catalysis , materials science , metallurgy
The reaction of ammonia‐ 15 N with benzaldehyde in 50% aq. methanol followed by slow removal of solvent led to a high yield of a crystalline product (benzylimine‐ 15 N). On reduction with sodium cyanoborohydride a good yield of benzylamine‐ 15 N was obtained. The synthetic usefulness of this compound is discussed.