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The preparation of dimethyl(7‐ 2 H 3 2‐oxoheptyl) phosphonate
Author(s) -
Taber Douglas F.,
Lee Charles H.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580140415
Subject(s) - phosphonate , chemistry , reagent , deuterium , methyl iodide , iodide , thromboxanes , radiochemistry , organic chemistry , medicinal chemistry , arachidonic acid , enzyme , physics , quantum mechanics
Dimethyl (7‐ 2 H 3 2‐oxoheptyl) phosphonate 4 has been prepared from 2 H 3 methyl iodide. The phosphonate should be a useful reagent for the synthesis of deuterium labelled prostaglandins and thromboxanes.