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Synthesis of some 2,3‐ 14 C‐quinoxaline derivatives
Author(s) -
Saari Walfred S.,
Lumma William C.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580140306
Subject(s) - quinoxaline , chemistry , glyoxylic acid , condensation , medicinal chemistry , stereochemistry , organic chemistry , physics , thermodynamics
6‐Chloro‐lH‐quinoxalin‐2‐one‐2,3‐ 14 C was prepared by the novel condensation of 4‐chloro‐1,2‐phenylenediamine with glyoxylic acid‐ 14 C (U). The labelled quinoxalinone was transformed further into 2,6‐dichloroquinoxaline‐2,3‐ 14 C and 6‐chloro‐2‐(1′‐piperazinyl)‐quinoxaline‐2,3‐ 14 C.