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Synthesis of high specific activity tritium‐labelled dotriacontane
Author(s) -
Houseman T. H.,
Binns S. H.,
Phillips K.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580140202
Subject(s) - chemistry , tritium , acetylide , specific activity , nuclear chemistry , catalysis , radiochemistry , medicinal chemistry , organic chemistry , enzyme , physics , nuclear physics
The tobacco smoke particulate phase marker dotriacontane was labelled with tritium at positions 15, 16, 17 and 18 by the catalytic reduction of dotriaconta‐15, 17‐diyne. This was obtained by oxidatively coupling hexadec‐1‐yne, in turn prepared by reaction of monosodium acetylide with myristyl bromide.