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Tritiation of low molecular weight alkanes and alkenes by self‐radiation induced exchange with HTO
Author(s) -
Long Mervyn A.,
Garnett John L.,
Meakin Christopher P.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580140110
Subject(s) - chemistry , tritium , radiochemistry , saturation (graph theory) , atmospheric temperature range , nuclear chemistry , nuclear physics , thermodynamics , physics , mathematics , combinatorics
The tritiation of a range of low molecular weight alkanes and alkenes has been investigated by self‐radiation induced exchange with HTO at room temperature and 115°. By comparison with the Wilzbach T 2 gas exposure procedure, the HTO method yields less byproducts and radiochemical purification of the parent compound is facilitated. With alkenes, saturation of the double bond is a competing process in the HTO procedure, however the significance of this side reaction decreases with increasing temperature of exchange. The HTO technique is shown to be suitable for tritiating a wide range of hydrocarbons to medium levels of specific activity.