Premium
Synthesis of 123 I‐4‐(3‐dimethylaminopropylamino)‐7‐iodoquinoline
Author(s) -
Bijl J. A.,
Kaspersen F. M.,
Lindner L.
Publication year - 1978
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580140107
Subject(s) - chemistry , iodide , radiochemistry , phosphate , nuclear chemistry , organic chemistry
123 I‐4‐(3‐dimethylaminopropylamino)‐7‐iodoquinoline (IAQ), a potential localizing agent for melanoma, was prepared by isotopic exchange between 123 I‐iodide and the phosphate or sulphate of IAQ. Yields up to 96% were obtained. The total time for preparation is restricted to 30 minutes.