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Synthesis of some 14 C‐labelled aziridine compounds, psychotropic agents
Author(s) -
Minato H.,
Nagasaki T.,
Katsuyama Y.,
Yokoshima T.,
Suga K.,
Ueda T.
Publication year - 1977
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.2580130110
Subject(s) - aziridine , chemistry , naphthalene , yield (engineering) , carbon 14 , psychotropic agent , ring (chemistry) , carbon fibers , medicinal chemistry , organic chemistry , psychology , materials science , physics , quantum mechanics , psychiatry , metallurgy , composite number , composite material
1‐Methyl‐2‐(2‐naphthyl)aziridine (1) and 1‐methyl–2‐(1,2,3,4‐tetrahydro‐2‐naphthyl)aziridine (II), psychotropic agents, were labelled by incorporating carbon‐14 into the carbon of the aziridine ring. Labelled products I and II were obtained in 32.4% and 14.4% radiochemical yield based on 2‐acetyl‐carbonyl‐ 14 C‐naphthalene (III), respectively.