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Amination and Synthesis of Some Nitronaphthyridines
Author(s) -
Woźniak Marian,
Tomula Maria
Publication year - 1993
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.199319930178
Subject(s) - chemistry , potassium permanganate , nitro , amination , adduct , ammonia , liquid ammonia , potassium , medicinal chemistry , organic chemistry , catalysis , alkyl
3‐Nitro and 3,6‐dinitro‐1,8‐naphthyridines 1 , 4 and 5 are dehydroaminated with a liquid ammonia solution of potassium permanganate to the corresponding 4‐amino‐substituted compounds 3 , 8 and 9 . The intermediate 4‐amino σ‐adducts 2 , 6 and 7 of the nitro‐1,8‐naphthyridines are detected by 1 H‐NMR spectroscopy. The syntheses of some nitro‐substituted naphthyridines are described.