Premium
Hetarylsulfoniumsalze durch Cyclisierung
Author(s) -
Gewald Karl,
Rehwald Matthias,
Gruner Margit
Publication year - 1993
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.199319930176
Subject(s) - chemistry , tetrahydrothiophene , anthranilic acid , acetophenone , salt (chemistry) , medicinal chemistry , organic chemistry , catalysis
Hetarylsulfonium Salts by Cyclization Reaction of tetrahydrothiophene with the N ‐(iodoacetyl)anthranilic acid derivatives 1a , b and 2‐(iodoacetylamino)acetophenone ( 1c ) yields the 1‐(2‐oxoquinolin‐3‐yl)tetrahydrothiophenium salts 3a – c in two steps. Analogously the heterocondensed 1‐(2‐oxopyridin‐3‐yl)tetrahydrothiophenium salts 6 and 7 can be prepared. The 1‐(3‐oxopyridazin‐4‐yl)‐ and 1‐(2‐oxopyridin‐3‐yl)tetrahydrothiophenium salts 10 , 13 , 16 , 18 are synthesized on the same way. From the tetrahydrothiophenium salt 3a the 3‐(alkylthio)‐4‐aminoquinolin‐2(1 H )‐ ones 19 arise.