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Benzocrown derivatives as ionophores for alkali cations, III. Synthesis of ring‐cleaved analogues of benzocrown ethers a novel method for building up crown ether rings
Author(s) -
Tőke László,
Bitter István,
Ágai Béla,
Hell Zoltán,
Lindner Ernő,
Tóth Klára,
Horváth Mária,
Szöllősy Áron,
Harfouch Salman,
Pungor Ernő
Publication year - 1988
Publication title -
liebigs annalen der chemie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 0170-2041
DOI - 10.1002/jlac.198819880810
Subject(s) - chemistry , ring (chemistry) , alkali metal , crown ether , cleavage (geology) , ether , hydrolysis , alkaline hydrolysis , combinatorial chemistry , stereochemistry , medicinal chemistry , inorganic chemistry , polymer chemistry , organic chemistry , ion , geotechnical engineering , fracture (geology) , engineering
Several ring‐cleaved analogues ( 9,11a,b ) of bis(benzo‐15‐crown‐5)‐urethanes ( 1a, b ) were prepared to study the change of complexation by electroanalytical methods. The syntheses of the title compounds ( 9,11a,b ) were accomplished in two ways: starting from 4‐nitroveratrole ( 2 ) via intermediates 3–8 to give compound 9 and by alkaline hydrolytic cleavage of 4‐nitrobenzocrown ethers ( 10a,b ) then by subsequent steps yielding 11a,b .