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An efficient synthesis of new pyrido[4′,3′:4,5]thieno[2,3‐ d ]‐pyrimidin‐4(3 H )‐one derivatives
Author(s) -
Hu YangGen,
Ding MingWu,
Zeng GuoPing
Publication year - 2008
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570450639
Subject(s) - chemistry , alkoxide , potassium carbonate , phenols , potassium , catalysis , medicinal chemistry , sodium carbonate , sodium , organic chemistry
The carbodiimides 5 , obtained from reactions of iminophosphorane 4 with aromatic isocyanates, reacted with amines, phenols or ROH to give 2‐substituted 5,6,7,8‐tetrahydropyrido[4′,3′:4,5]thieno[2,3‐ d ]‐pyrimidin‐4(3 H )‐one 7 in the presence of catalytic amount of sodium alkoxide or solid potassium carbonate in satisfactory yields.