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Potassium carbonate, a support for the green synthesis of azoles and diazines
Author(s) -
Kidwai M.,
Venkataramanan R.,
Dave B.
Publication year - 2002
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570390530
Subject(s) - chemistry , potassium carbonate , yield (engineering) , potassium , carbonate , solvent , aqueous solution , green chemistry , organic chemistry , medicinal chemistry , combinatorial chemistry , reaction mechanism , catalysis , metallurgy , materials science
Abstract A novel potassium carbonate mediated synthesis of 2‐amino‐1,3‐thia/oxa zoles, 2‐amino‐1,3,4‐thia/oxa diazines and 2‐hydrazino‐1,3,4‐thiadiazines has been described here. The use of K 2 CO 3 allows for an aqueous workup thereby eliminating the organic solvent from both the reaction step and post reaction stage, without compromising the yield and reaction time.